After receiving Spravato (esketamine) treatment, your next steps are crucial for safety and to support the therapeutic effects of the medication. Spravato is a fast-acting medication used to treat treatment-resistant depression and is administered under medical supervision in a clinic. Here’s what to expect and do afterward:
1. Rest and Recovery
Spravato can cause side effects like:
- Dizziness
- Dissociation (feeling disconnected from yourself)
- Fatigue or sleepiness
These are normal and usually wear off within a few hours. It’s best to go home and rest in a quiet, calm environment. Avoid bright lights, loud noises, or stressful activities.
2. Do Not Drive or Operate Machinery
Because Spravato affects your alertness and coordination, you are not allowed to drive for the rest of the day. Make sure you have someone to drive you home after each treatment session. This is required by FDA guidelines for patient safety.
3. Stay Hydrated and Eat Lightly
After treatment, drink water and eat something light if you feel up to it. Avoid caffeine, alcohol, or heavy meals immediately after your session, unless directed otherwise by your provider.
4. Monitor Your Mood and Symptoms
It can be helpful to keep a journal or use a mood-tracking app to record how you feel in the hours and days after treatment. Write down:
- Emotional changes
- Sleep patterns
- Side effects
- Positive improvements
This information helps your psychiatrist or mental health provider adjust your treatment plan if needed.
5. Follow Up with Your Mental Health Provider
Spravato is most effective when combined with ongoing psychiatric support. You’ll likely have several sessions scheduled during the first few weeks. Be open with your provider about:
- How you’re feeling
- Any changes in side effects
- Whether you’re noticing improvements
6. Avoid Alcohol, Cannabis, or Other Sedatives
Unless prescribed or cleared by your doctor, avoid using substances that may interfere with Spravato or increase sedation.
7. Be Patient – Results Take Time
Spravato works differently than traditional antidepressants. Some people feel better after just a few treatments, while others need several weeks to notice improvements. Stay committed to the treatment plan, and don’t skip sessions unless advised.
When to Contact Your Provider
Call your provider right away if you experience:
- Unusual thoughts or behaviors
- Severe confusion or agitation
- Chest pain or trouble breathing
- Symptoms that feel worse instead of better
In Summary
After a Spravato treatment session, prioritize safety, self-care, and communication with your provider. The journey to feeling better is a process, and with the right support, Spravato can be a powerful part of your recovery.