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Is Spravato Addictive?

Spravato (esketamine) is not considered addictive when used under medical supervision. At IM Wellness, all Spravato treatments are carefully administered in a certified clinical setting to ensure safety, effectiveness, and responsible use.

Understanding How Spravato Works

Spravato is a nasal spray containing esketamine, a medication derived from ketamine. Unlike traditional antidepressants that affect serotonin or dopamine, Spravato targets the NMDA receptors in the brain, helping to restore healthy brain activity and reduce symptoms of treatment-resistant depression.

Because it works through a different mechanism, Spravato offers rapid relief for patients who haven’t responded to other medications. However, its unique action is also why it’s administered only in a controlled clinic environment.

Why Spravato Has Low Addiction Risk

While ketamine (its parent compound) can be misused when taken recreationally, Spravato is formulated and prescribed differently:

  • It’s given only in certified medical clinics like IM Wellness.
  • Patients cannot take it home or self-administer it.
  • Each treatment is monitored by healthcare professionals for at least two hours after dosing.
  • The dosage and frequency are strictly regulated by the FDA’s REMS program.

These safeguards make the risk of addiction or dependence extremely low.

What Patients Can Expect at IM Wellness

At IM Wellness, our Spravato treatment program is designed with patient safety and comfort as top priorities. During your visit:

  • You’ll receive your Spravato dose under medical supervision.
  • Our clinicians will monitor your response, blood pressure, and overall well-being.
  • We provide a relaxing environment where you can recover before leaving the clinic.
  • Your progress is reviewed after each session to ensure long-term effectiveness and stability.

This structured, evidence-based approach helps prevent misuse while improving mental health outcomes.

Research on Spravato and Addiction

Clinical studies and post-treatment data have shown no strong evidence of Spravato leading to addiction when used as prescribed. Most patients do not experience cravings or withdrawal symptoms. In fact, Spravato often helps patients regain control over their lives by effectively reducing depression and suicidal thoughts.

Bottom Line

Spravato is safe, effective, and non-addictive when administered correctly.
At IM Wellness, our mission is to help patients overcome depression using the most advanced and medically supervised treatments available. If you’re considering Spravato therapy, consult our experienced team to learn how it can fit into your personalized treatment plan.


At Insight Mental Wellness, we offer personalized mental health care designed to support your journey toward recovery and stability.

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